I am sure you are all well aware that the weight loss supplement industry in a billion dollar industry, but with literally thousands of fat-burning supplements on the market, how on earth do you know which one to choose?

Each and every supplement company totes their product as the last magic little pill you will ever need to achieve your dream physique; however, this may not always be the case. There is no magic pill which will make you miraculously drop that unwanted poundage. Weight loss is largely dependent upon a calorie restricted healthy diet coupled with a rigorous training regimen. Supplements merely assist to speed up the process. In other words, if you are not dieting correctly and slacking on your training, no fat burner is going to help you lose weight by itself.

So back to the original question, once you have your diet and training on point, how do you know which weight loss supplement to use? While there are a number of brands on the market which have excellent supplements, I always judge a product by the ingredients it contains.

In this article we are going to look at some of the most powerful metabolism-stimulating ingredients which are commonly found in fat burners. But first, let me briefly explain why it is important to boost your metabolism when you are looking to lose weight.


Every chemical reaction which occurs in the body to sustain life, whether anabolic (building of molecules) or catabolic (breaking down of complex substrates) require energy to occur. The sum of energy required to perform these reactions is known as metabolism. Metabolism is a highly intricate system of chemical reactions in the body which can be affected by a number of outside phenomena including the energy status of the body, hormone signalling as well as how and when these reactions take place etcetera.

The main concern for us however, is the energy input versus energy output or as you may have heard it stated before, the amount of calories you consume versus the amount of calories you burn. If you burn more calories than what you consume, your body will go into a catabolic state where it will begin to break down cells, largely in the form of adipose tissue (or fat). With that said, I am sure you now understand why it is necessary to increase your metabolic rate when trying to lose weight.



Caffeine is an extremely powerful stimulant which affects the central nervous system (CNS). It works by inhibiting phosphodiesterase enzymes which then prevents the breakdown of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). These chemical regulate signal transduction in cells. Basically, the more effectively these signal chemicals work, the better the metabolism will function. Not just that, it will also help with the oxidation of fatty tissue.


Caffeine intake is largely dependent on personal tolerances as this stimulant affects people differently. According to studies, it is suggested to supplement with 1-3mg per kilogram of lean body mass. It can be taken throughout the day but we suggest that you do not take any doses after 5pm or you may battle with insomnia.

After roughly 2 weeks of continuous use, it is suggested to stop use for a few days to prevent tolerance buildup.


Along with caffeine, green tea is probably the most common ingredient found in fat-burning supplements. The active ingredient which is responsible for its metabolic-boosting effects is epigallocathechin gallate (EGCG). Epigallocathechin gallate increases the activity of neurotransmitters like epinephrine and dopamine, which in turn enhances metabolic rate. EGCG also has powerful antioxidant effects and acts as a anti-carcinogenic agent.


According to studies, the effective dosing range of green tea extract is 150-250mg per day. The serving dose will vary from product to product depending on the concentration of EGCG in the product.


Capsaicin is the compound which is responsible for the ‘burn’ found in hot peppers. The reason for supplemental capsaicin is that it is impractical to reach nominal doses through hot pepper consumption, thus concentrated doses are more effective.

According to scientific studies, the reason why capsaicin increases metabolic expenditure is because of its effect on beta-adrenergic stimulation. The research suggests that the increase in energy expenditure along with the simultaneous decrease in respiratory quotient positively affects the oxidation of adipose tissue.


The optimal dose of capsaicin is between 2-3mg per serving and can be take up to 3 times per day. It can be consumed at any time, however, if you find you battle with gastric irritation, then make sure to take it with meals.


PQQ is an ingredient you may have never heard of, but this compound can add a whole new dimension to fat burning. It is quinoprotein which is primarily obtained from fermented soybeans. The theory behind the method of action of PQQ is that it is able to elevate metabolic rate through the increasing of mitochondria within the cells of the body. This is known as mitochondrial biogenesis. PQQ also increases the production of irisin and it acts as a cellular messenger that mimics the basic effects of physical activity.


Studies suggest that 20-60mg per day is effective and safe.


Chronicle Nutrition LipoSwitch & LipoActivator

By using correct doses of caffeine and green tea LipoSwitch has been designed to release fat from cells, which can be utilized as energy throughout the day. LipoSwitch can help you torch fat by ramping up your metabolism while burning energy released from fat cells. All this thanks to our clinically researched formula.

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